Scans have confirmed Essendon midfielder Andrew McGrath suffered a grade two posterior cruciate ligament (PCL) injury in Saturday night's loss to Richmond at Optus Stadium.
McGrath was subbed out of the game after sustaining the injury in the first quarter.
General manager of football Josh Mahoney said the injury would likely see the co-vice captain sidelined for eight to 12 weeks.
“We are really disappointed for Andy who was putting together a consistent season to date as part of our midfield group,” Mahoney said.
“Andy is a true professional who will be very driven to see a return to play as soon as possible. We know he will attack his rehabilitation program and continue to contribute to the team while not playing.”