Scans have confirmed hamstring injuries to Jye Caldwell and Jake Stringer, with the pair set to be sidelined over the coming weeks.
General manager of football Josh Mahoney provided an update on the pair.
“Jye was tracking well in his recovery and was looking to be available again for selection in the coming weeks. Unfortunately at the end of a training session late last week, he suffered a high-grade hamstring strain," Mahoney said.
“Given the position of the strain in his hamstring and the previous injury he sustained earlier in the season, the club will take a conservative approach with his recovery which may involve surgery, and as such we will delay putting a timeframe on his availability.
“It’s disappointing for Jye who has settled in so well at the club since arriving last year, but he is an important and long-term player for Essendon, and we will fully support him in his recovery.
“Jake was subbed out of the game on Saturday against the Giants, and scans have since confirmed he suffered a hamstring strain.
“This is likely to be a standard recovery and we expect Jake back in approximately three to four weeks.”
The club will provide a full performance and injury update on Wednesday.