Jobe Watson and Travis Colyer will return to the Essendon line-up for the match against Fremantle on Sunday.
The pair replace Craig Bird and Josh Green (foot).
Heath Hocking, Kyle Langford and Shaun McKernan will be the emergencies.
The Club will pay tribute to retiring champions Jobe Watson, James Kelly and Brent Stanton throughout the match.
Ten thousand Watson face masks will also be handed out to fans to use throughout the game, and specifically at the fourth minute of each quarter.
Click here to download your Watson face mask now.
Round 23
Essendon v Fremantle
Sunday August 27
Etihad Stadium
1:10pm
In: Jobe Watson, Travis Colyer
Out: Craig Bird, Josh Green (foot)
B: David Myers, Michael Hartley, Mark Baguley
HB: Andrew McGrath, Patrick Ambrose, Conor McKenna
C: James Kelly, Darcy Parish, Brendon Goddard
HF: Zach Merrett, Cale Hooker, Martin Gleeson
F: Josh Begley, Joe Daniher, James Stewart
R: Tom Bellchambers, David Zaharakis, Dyson Heppell
I: Jobe Watson, Travis Colyer, Jayden Laverde, Anthony McDonald-Tipungwuti
E: Kyle Langford, Heath Hocking, Shaun McKernan